Contraindicated (1)pentobarbital decreases levels of vandetanib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Avoid coadministration with potent CYP3A4 inducers; these medication cut down exposure to vandetanib by nearly 40%.pentobarbital decreases amounts of panobinostat by affecting hepatic/intestinal enzyme CYP3A4 me
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pentobarbital will minimize the extent or effect of gefitinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism.pentobarbital will lessen the level or influence of amlodipine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.pentobarbital will reduce the extent or result of conivaptan by impacting hepatic/i